FLI-06

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For Research Use Only | Not For Clinical Use
CATAP313967189
CAS313967-18-9
Molecular Weight438.52
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C

1b-Annulated 1,4-dihydropyridines as Notch Inhibitors

Jorge E Gómez-Galeno, Cecilia Hurtado, Jiongjia Cheng, Ceren Yardimci, Mark Mercola, John R Cashman

Bioorg Med Chem Lett. 2018 Nov 1;28(20):3363-3367.

PMID: 30201292

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1FLI-06 Intercepts Notch Signaling And Suppresses The Proliferation And Self-renewal Of Tongue Cancer Cells

Rui-Huan Gan, Li-Song Lin, Jing Xie, Li Huang, Lin-Can Ding, Bo-Hua Su, Xian-E Peng, Da-Li Zheng, You-Guang Lu

Onco Targets Ther. 2019 Sep 18;12:7663-7674.

PMID: 31571917

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1FLI-06 Suppresses Proliferation, Induces Apoptosis and Cell Cycle Arrest by Targeting LSD1 and Notch Pathway in Esophageal Squamous Cell Carcinoma Cells

Zhaoming Lu, Yandan Ren, Mengying Zhang, Tianli Fan, Yang Wang, Qi Zhao, Hong-Min Liu, Wen Zhao, Guiqin Hou

Biomed Pharmacother. 2018 Nov;107:1370-1376.

PMID: 30257352

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1Inhibition of Cargo Export at ER Exit Sites and the trans-Golgi Network by the Secretion Inhibitor FLI-06

Yoji Yonemura, Xiaolin Li, Katja Müller, Andreas Krämer, Paul Atigbire, Torben Mentrup, Talitha Feuerhake, Torsten Kroll, Olga Shomron, Richard Nohl, Hans-Dieter Arndt, Christian Hoischen, Peter Hemmerich, etc.

J Cell Sci. 2016 Oct 15;129(20):3868-3877.

PMID: 27587840

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1MFAP5 Facilitates the Aggressiveness of Intrahepatic Cholangiocarcinoma by Activating the Notch1 Signaling Pathway

Jian-Hui Li, Xiao-Xu Zhu, Fu-Xi Li, Chen-Song Huang, Xi-Tai Huang, Jie-Qin Wang, Zhuo-Xing Gao, Shi-Jin Li, Qiong-Cong Xu, Wei Zhao, Xiao-Yu Yin

J Exp Clin Cancer Res. 2019 Nov 27;38(1):476.

PMID: 31775892

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