GW9508

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For Research Use Only | Not For Clinical Use
CATAP885101893-B
CAS885101-89-3
MDL NumberMFCD09753282
Molecular Weight347.41
InChI KeyDGENZVKCTGIDRZ-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: >20 mg/mL
Assay≥98% (HPLC)
Formwhite powder
Size5MG, 25MG
Storage Conditions2-8°C

1Activation of GPR40 Produces Mechanical Antiallodynia via the Spinal Glial interleukin-10/β-endorphin Pathway

Xiao-Fang Mao, Hai-Yun Wu, Xue-Qi Tang, Usman Ali, Hao Liu, Yong-Xiang Wang

J Neuroinflammation. 2019 Apr 13;16(1):84.

PMID: 30981281

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1GPR40 Receptor Activation Promotes Tight Junction Assembly in Airway Epithelial Cells via AMPK-dependent Mechanisms

Aekkacha Moonwiriyakit, Panisara Wattanaphichet, Varanuj Chatsudthipong, Chatchai Muanprasat

Tissue Barriers. 2018;6(2):1-12.

PMID: 29913106

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1G-protein-coupled Receptor 40 Agonist GW9508 Potentiates Glucose-Stimulated Insulin Secretion Through Activation of Protein Kinase Cα and ε in INS-1 Cells

Takuya Hashimoto, Hideo Mogami, Daisuke Tsuriya, Hiroshi Morita, Shigekazu Sasaki, Tatsuro Kumada, Yuko Suzuki, Tetsumei Urano, Yutaka Oki, Takafumi Suda

PLoS One. 2019 Sep 9;14(9):e0222179.

PMID: 31498851

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1GW9508 Inhibits Insulin Secretion by Activating ATP-sensitive Potassium Channels in Rat Pancreatic β-cells

Yu-Feng Zhao, Li Wang, Dingjun Zha, Li Qiao, Lianjun Lu, Jun Yu, Ping Qu, Qiang Sun, Jianhua Qiu, Chen Chen

J Mol Endocrinol. 2013 Jun 1;51(1):69-77.

PMID: 23628491

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1Pharmacological Stimulation of G-protein Coupled Receptor 40 Alleviates Cytokine-Induced Epithelial Barrier Disruption in Airway Epithelial Calu-3 Cells

Aekkacha Moonwiriyakit, Michael Koval, Chatchai Muanprasat

Int Immunopharmacol. 2019 Aug;73:353-361.

PMID: 31129422

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