CAS 885101-89-3 GW9508 - Analytical Products / Alfa Chemistry

CAT	AP885101893-B
CAS	885101-89-3
MDL Number	MFCD09753282
Molecular Weight	347.41
InChI Key	DGENZVKCTGIDRZ-UHFFFAOYSA-N

Description	≥98% (HPLC)
Solubility	DMSO: >20 mg/mL
Assay	≥98% (HPLC)
Form	white powder
Size	5MG, 25MG
Storage Conditions	2-8°C

1

Activation of GPR40 Produces Mechanical Antiallodynia via the Spinal Glial interleukin-10/β-endorphin Pathway

Xiao-Fang Mao, Hai-Yun Wu, Xue-Qi Tang, Usman Ali, Hao Liu, Yong-Xiang Wang

J Neuroinflammation. 2019 Apr 13;16(1):84.

PMID: 30981281

1

GPR40 Receptor Activation Promotes Tight Junction Assembly in Airway Epithelial Cells via AMPK-dependent Mechanisms

Aekkacha Moonwiriyakit, Panisara Wattanaphichet, Varanuj Chatsudthipong, Chatchai Muanprasat

Tissue Barriers. 2018;6(2):1-12.

PMID: 29913106

1

G-protein-coupled Receptor 40 Agonist GW9508 Potentiates Glucose-Stimulated Insulin Secretion Through Activation of Protein Kinase Cα and ε in INS-1 Cells

Takuya Hashimoto, Hideo Mogami, Daisuke Tsuriya, Hiroshi Morita, Shigekazu Sasaki, Tatsuro Kumada, Yuko Suzuki, Tetsumei Urano, Yutaka Oki, Takafumi Suda

PLoS One. 2019 Sep 9;14(9):e0222179.

PMID: 31498851

1

GW9508 Inhibits Insulin Secretion by Activating ATP-sensitive Potassium Channels in Rat Pancreatic β-cells

Yu-Feng Zhao, Li Wang, Dingjun Zha, Li Qiao, Lianjun Lu, Jun Yu, Ping Qu, Qiang Sun, Jianhua Qiu, Chen Chen

J Mol Endocrinol. 2013 Jun 1;51(1):69-77.

PMID: 23628491

1

Pharmacological Stimulation of G-protein Coupled Receptor 40 Alleviates Cytokine-Induced Epithelial Barrier Disruption in Airway Epithelial Calu-3 Cells

Aekkacha Moonwiriyakit, Michael Koval, Chatchai Muanprasat

Int Immunopharmacol. 2019 Aug;73:353-361.

PMID: 31129422

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