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For Research Use Only | Not For Clinical Use
Molecular Weight654.72
Description≥98% (HPLC)
SolubilityDMSO: 15 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Size5MG, 25MG
Storage Conditions2-8°C

1Inhibition of PGE 2/EP4 receptor signaling enhances oxaliplatin efficacy in resistant colon cancer cells through modulation of oxidative stress

Huakang Huang, Oladimeji Aladelokun, Takayasu Ideta, Charles Giardina, Lee M Ellis, Daniel W Rosenberg

Sci Rep. 2019 Mar 20;9(1):4954.

PMID: 30894570

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1Opposing effects of prostaglandin E 2 receptors EP3 and EP4 on mouse and human β-cell survival and proliferation

Bethany A Carboneau, Jack A Allan, Shannon E Townsend, Michelle E Kimple, Richard M Breyer, Maureen Gannon

Mol Metab. 2017 Apr 5;6(6):548-559.

PMID: 28580285

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1Prostaglandin E 2 Receptor Antagonist with Antimicrobial Activity against Methicillin-Resistant Staphylococcus aureus

Mélanie A C Ikeh, Paul L Fidel Jr, Mairi C Noverr

Antimicrob Agents Chemother. 2018 Feb 23;62(3):e01920-17.

PMID: 29263068

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1The EP4 Antagonist, L-161,982, Induces Apoptosis, Cell Cycle Arrest, and Inhibits Prostaglandin E2-induced Proliferation in Oral Squamous Carcinoma Tca8113 Cells

Xiaohui Li, Bo Yang, Guoxu Han, Weizhong Li

J Oral Pathol Med. 2017 Nov;46(10):991-997.

PMID: 28342204

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1The EP4 Receptor Antagonist, L-161,982, Blocks Prostaglandin E2-induced Signal Transduction and Cell Proliferation in HCA-7 Colon Cancer Cells

Durga Prasad Cherukuri, Xiao B O Chen, Anne-Christine Goulet, Robert N Young, Yongxin Han, Ronald L Heimark, John W Regan, Emmanuelle Meuillet, Mark A Nelson

Exp Cell Res. 2007 Aug 15;313(14):2969-79.

PMID: 17631291

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