INQUIRY Add to cart
For Research Use Only | Not For Clinical Use
Molecular Weight517.54
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Size5MG, 25MG
Storage Conditions2-8°C

1[Effects of Ubiquitination on the Expression of BCL6 Protein,Cell Proliferation and Apoptosis in K562/G01 Cells]

Hui-Min Tang, Wei Ding, Yi-Han Ding, Jing-Jing Wu, Yu-Feng Li

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2019 Apr;27(2):379-384.

PMID: 30998141

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1Inhibition of Ubiquitin-Specific Protease 2 Causes Accumulation of Reactive Oxygen Species, Mitochondria Dysfunction, and Intracellular ATP Decrement in C2C12 Myoblasts

Mayuko Hashimoto, Natsuko Saito, Haru Ohta, Kumiko Yamamoto, Asuka Tashiro, Kosuke Nakazawa, Osamu Inanami, Hiroshi Kitamura

Physiol Rep. 2019 Jul;7(14):e14193.

PMID: 31353872

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1Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates Cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models

Mindy I Davis, Rajan Pragani, Jennifer T Fox, Min Shen, Kalindi Parmar, Emily F Gaudiano, Li Liu, Cordelle Tanega, Lauren McGee, Matthew D Hall, Crystal McKnight, Paul Shinn, Henrike Nelson, Debasish Chattopadhyay, etc.

J Biol Chem. 2016 Nov 18;291(47):24628-24640.

PMID: 27681596

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1The Deubiquitylase USP2 Maintains ErbB2 Abundance via Counteracting Endocytic Degradation and Represents a Therapeutic Target in ErbB2-positive Breast Cancer

Jinrui Zhang, Shuyan Liu, Qiong Li, Yulin Shi, Yueguang Wu, Fang Liu, Shanshan Wang, Mohamed Y Zaky, Waleed Yousuf, Qianhui Sun, Dong Guo, Taishu Wang, Yingqiu Zhang, Yang Wang, Man Li, Han Liu

Cell Death Differ. 2020 Apr 23.

PMID: 32327714

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