NS 1619

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For Research Use Only | Not For Clinical Use
CATAP153587010
CAS153587-01-0
MDL NumberMFCD00928190
Molecular Weight362.23
InChI KeyYLFMCMWKHSDUCT-UHFFFAOYSA-N
Descriptionpowder
Solubility45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47 mg/mL; ethanol: 26.6 mg/mL; 0.1 M NaOH: 5.2 mg/mL; DMSO: 5.3 mg/mL; H2O: insoluble
Colorwhite
Formpowder
Size5MG, 25MG

1Inhibition of Guinea Pig Detrusor Contraction by NS-1619 Is Associated With Activation of BKCa and Inhibition of Calcium Currents

J H Sheldon, N W Norton, T M Argentieri

J Pharmacol Exp Ther. 1997 Dec;283(3):1193-200.

PMID: 9399993

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1Ion Channel Modulation by NS 1619, the Putative BKCa Channel Opener, in Vascular Smooth Muscle

G Edwards, A Niederste-Hollenberg, J Schneider, T Noack, A H Weston

Br J Pharmacol. 1994 Dec;113(4):1538-47.

PMID: 7534190

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1NS 1619 Activates Ca2+-activated K+ Currents in Rat Vas Deferens

Y Huang, C W Lau, I H Ho

Eur J Pharmacol. 1997 Apr 23;325(1):21-7.

PMID: 9151934

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1Preconditioning With the BK

Hongyan Dai, Meifang Wang, Parag N Patel, Theodore Kalogeris, Yajun Liu, William Durante, Ronald J Korthuis

Am J Physiol Heart Circ Physiol. 2017 Nov 1;313(5):H988-H999.

PMID: 28822969

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1The Mitochondrial Ca2+-activated K+ Channel Activator, NS 1619 Inhibits L-type Ca2+ Channels in Rat Ventricular Myocytes

Won Sun Park, Sung Hyun Kang, Youn Kyoung Son, Nari Kim, Jae-Hong Ko, Hyoung Kyu Kim, Eun A Ko, Chi Dae Kim, Jin Han

Biochem Biophys Res Commun. 2007 Oct 12;362(1):31-36.

PMID: 17698036

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