NS1643

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For Research Use Only | Not For Clinical Use
CATAP448895372
CAS448895-37-2
Structure
MDL NumberMFCD08705418
Molecular Weight380.24
InChI KeyNJFVQMRYJZHGME-UHFFFAOYSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: ≥20 mg/mL
Assay≥98% (HPLC)
Colorwhite to off-white
Formsolid
Size5MG, 25MG
Storage Conditions2-8°C

1Effects of Potassium Channel Openers in the Isolated Perfused Hypokalaemic Murine Heart

M J Killeen, G Thomas, S-P Olesen, J Demnitz, K S Stokoe, A A Grace, C L-H Huang

Acta Physiol (Oxf). 2008 May;193(1):25-36.

PMID: 18005217

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1Mechanism of Action of a Novel Human Ether-A-Go-Go-Related Gene Channel Activator

Oscar Casis, Søren-Peter Olesen, Michael C Sanguinetti

Mol Pharmacol. 2006 Feb;69(2):658-65.

PMID: 16284303

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1NS1643 Interacts Around L529 of hERG to Alter Voltage Sensor Movement on the Path to Activation

Jiqing Guo, Yen May Cheng, James P Lees-Miller, Laura L Perissinotti, Tom W Claydon, Christina M Hull, Samrat Thouta, Daniel E Roach, Serdar Durdagi, Sergei Y Noskov, Henry J Duff

Biophys J. 2015 Mar 24;108(6):1400-1413.

PMID: 25809253

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1Pharmacological Activation of Kv11.1 in Transgenic Long QT-1 Rabbits

Bo Hjorth Bentzen, Sophia Bahrke, Kezhong Wu, Anders Peter Larsen, Katja E Odening, Gerlind Franke, Karin Storm vańs Gravesande, Jürgen Biermann, Xuwen Peng, Gideon Koren, Manfred Zehender, Christoph Bode, etc.

J Cardiovasc Pharmacol. 2011 Feb;57(2):223-30.

PMID: 21135701

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1Potassium Channel Activity Controls Breast Cancer Metastasis by Affecting β-catenin Signaling

Eun-Kyoung Breuer, Daniela Fukushiro-Lopes, Annika Dalheim, Miranda Burnette, Jeremiah Zartman, Simon Kaja, Claire Wells, Loredana Campo, Kimberly J Curtis, Ricardo Romero-Moreno, Laurie E Littlepage, Glen L Niebur, etc.

Cell Death Dis. 2019 Feb 21;10(3):180.

PMID: 30792401

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