NS309

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For Research Use Only | Not For Clinical Use
CATAP18711165
CAS18711-16-5
Structure
MDL NumberMFCD06798346
Molecular Weight231.04
InChI KeyCVOUSAVHMDXCKG-UHFFFAOYSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: 22 mg/mL
Assay≥98% (HPLC)
Coloryellow
Formsolid
Size5MG, 25MG
Storage Conditions2-8°C

1Heterocellular Contact Can Dictate Arterial Function

Xiaohong Shu, Claire A Ruddiman, T C Stevenson Keller 4th, Alexander S Keller, Yang Yang, Miranda E Good, Angela K Best, Linda Columbus, Brant E Isakson

Circ Res. 2019 May 10;124(10):1473-1481.

PMID: 30900949

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1NS309 Decreases Rat Detrusor Smooth Muscle Membrane Potential and Phasic Contractions by Activating SK3 Channels

Shankar P Parajuli, Kiril L Hristov, Rupal P Soder, Whitney F Kellett, Georgi V Petkov

Br J Pharmacol. 2013 Apr;168(7):1611-25.

PMID: 23145946

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1NS309 Restores EDHF-type Relaxation in Mesenteric Small Arteries From Type 2 Diabetic ZDF Rats

E Brøndum, H Kold-Petersen, U Simonsen, Christian Aalkjaer

Br J Pharmacol. 2010 Jan;159(1):154-65.

PMID: 20015296

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1The Potassium SK Channel Activator NS309 Protects Against Experimental Traumatic Brain Injury Through Anti-Inflammatory and Immunomodulatory Mechanisms

Tao Chen, Jie Zhu, Chun-Hua Hang, Yu-Hai Wang

Front Pharmacol. 2019 Nov 29;10:1432.

PMID: 31849677

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1Urodynamic Effects of Intravesical Administration of the New small/intermediate Conductance Calcium Activated Potassium Channel Activator NS309 in Freely Moving, Conscious Rats

Raj Kumar Pandita, Lars Christian B Rønn, Bo Skaaning Jensen, Karl-Erik Andersson

J Urol. 2006 Sep;176(3):1220-4.

PMID: 16890729

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