NS5806

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For Research Use Only | Not For Clinical Use
CATAP426834697
CAS426834-69-7
MDL NumberMFCD18432708
Molecular Weight574.07
InChI KeyUZWJWROOLOOCPQ-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: >30 mg/mL
Assay≥98% (HPLC)
Colorwhite to faint yellow
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C

1A Transient Outward Potassium Current Activator Recapitulates the Electrocardiographic Manifestations of Brugada Syndrome

Kirstine Calloe, Jonathan M Cordeiro, José M Di Diego, Rie S Hansen, Morten Grunnet, Søren Peter Olesen, Charles Antzelevitch

Cardiovasc Res. 2009 Mar 1;81(4):686-94.

PMID: 19073629

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1Comparison of the Effects of a Transient Outward Potassium Channel Activator on Currents Recorded From Atrial and Ventricular Cardiomyocytes

Kirstine Calloe, Eyal Nof, Thomas Jespersen, José M Di Diego, Natalie Chlus, Søren-Peter Olesen, Charles Antzelevitch, Jonathan M Cordeiro

J Cardiovasc Electrophysiol. 2011 Sep;22(9):1057-66.

PMID: 21457383

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1Differential responses of rabbit ventricular and atrial transient outward current (I to) to the I to modulator NS5806

Hongwei Cheng, Mark B Cannell, Jules C Hancox

Physiol Rep. 2017 Mar;5(5):e13172.

PMID: 28270595

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1Hippocampal A-type Current and Kv4.2 Channel Modulation by the Sulfonylurea Compound NS5806

Katrin Witzel, Paul Fischer, Robert Bähring

Neuropharmacology. 2012 Dec;63(8):1389-403.

PMID: 22964468

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1NS5806 Induces Electromechanically Discordant Alternans and Arrhythmogenic Voltage-Calcium Dynamics in the Isolated Intact Rabbit Heart

Sufen Wang, Moisés Rodríguez-Mañero, Sergio H Ibarra-Cortez, Bahij Kreidieh, Laura Valderrábano, Majd Hemam, Liliana Tavares, Elvin Blanco, Miguel Valderrábano

Front Physiol. 2019 Dec 20;10:1509.

PMID: 31920713

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