CAS 383907-43-5 NSC 663284 - Analytical Products / Alfa Chemistry

CAT	AP383907435
CAS	383907-43-5
Structure
MDL Number	MFCD08276924
Molecular Weight	321.76
InChI Key	BMKPVDQDJQWBPD-UHFFFAOYSA-N

Description	≥98% (HPLC), solid
Solubility	DMSO: ≥10 mg/mL; H2O: insoluble
Assay	≥98% (HPLC)
Color	red
Form	solid
Size	5MG, 25MG
Storage Conditions	2-8°C

1

Discovery and Biological Evaluation of a New Family of Potent Inhibitors of the Dual Specificity Protein Phosphatase Cdc25

J S Lazo, D C Aslan, E C Southwick, K A Cooley, A P Ducruet, B Joo, A Vogt, P Wipf

J Med Chem. 2001 Nov 22;44(24):4042-9.

PMID: 11708908

1

Dual G1 and G2 Phase Inhibition by a Novel, Selective Cdc25 Inhibitor 6-chloro-7-[corrected](2-morpholin-4-ylethylamino)-quinoline-5,8-dione

Lixia Pu, Andrew A Amoscato, Mark E Bier, John S Lazo

J Biol Chem. 2002 Dec 6;277(49):46877-85.

PMID: 12356752

1

Identification of Highly Potent and Selective Cdc25 Protein Phosphatases Inhibitors From Miniaturization Click-Chemistry-Based Combinatorial Libraries

Lanlan Jing, Gaochan Wu, Xia Hao, Fisayo A Olotu, Dongwei Kang, Chin Ho Chen, Kuo-Hsiung Lee, Mahmoud E S Soliman, Xinyong Liu, Yuning Song, Peng Zhan

Eur J Med Chem. 2019 Dec 1;183:111696.

PMID: 31541869

1

NAD(P)H:quinone oxidoreductase-1-dependent and -Independent Cytotoxicity of Potent Quinone Cdc25 Phosphatase Inhibitors

Yusheng Han, Hongmei Shen, Brian I Carr, Peter Wipf, John S Lazo, Su-shu Pan

J Pharmacol Exp Ther. 2004 Apr;309(1):64-70.

PMID: 14718602

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