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For Research Use Only | Not For Clinical Use
MDL NumberMFCD22666390
Molecular Weight421.36
Description≥98% (HPLC)
SolubilityH2O: 5 mg/mL (clear solution)
Assay≥98% (HPLC)
Colorwhite to beige
Size5MG, 25MG
Storage Conditionsroom temp

1Nsc23925 Prevents the Development of Paclitaxel Resistance by Inhibiting the Introduction of P-glycoprotein and Enhancing Apoptosis

Xiaoqian Yang, Jacson Shen, Yan Gao, Yong Feng, Yichun Guan, Zhan Zhang, Henry Mankin, Francis J Hornicek, Zhenfeng Duan

Int J Cancer. 2015 Oct 15;137(8):2029-39.

PMID: 25904021

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1NSC23925 Prevents the Emergence of Multidrug Resistance in Ovarian Cancer in Vitro and in Vivo

Xiaoqian Yang, Yong Feng, Yan Gao, Jacson Shen, Edwin Choy, Gregory Cote, David Harmon, Zhan Zhang, Henry Mankin, Francis J Hornicek, Zhenfeng Duan

Gynecol Oncol. 2015 Apr;137(1):134-42.

PMID: 25677062

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1NSC23925, Identified in a High-Throughput Cell-Based Screen, Reverses Multidrug Resistance

Zhenfeng Duan, Edwin Choy, Francis J Hornicek

PLoS One. 2009 Oct 12;4(10):e7415.

PMID: 19823672

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1Prevention of Multidrug Resistance (MDR) in Osteosarcoma by NSC23925

X Yang, P Yang, J Shen, E Osaka, E Choy, G Cote, D Harmon, Z Zhang, H Mankin, F J Hornicek, Z Duan

Br J Cancer. 2014 Jun 10;110(12):2896-904.

PMID: 24853187

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1Synthesis and Evaluation of (2-(4-methoxyphenyl)-4-quinolinyl)(2-piperidinyl)methanol (NSC23925) Isomers to Reverse Multidrug Resistance in Cancer

Zhenfeng Duan, Xin Li, Haoxi Huang, Wei Yuan, Shao-Liang Zheng, Xianzhe Liu, Zhan Zhang, Edwin Choy, David Harmon, Henry Mankin, Francis Hornicek

J Med Chem. 2012 Apr 12;55(7):3113-21.

PMID: 22400811

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