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OL-135

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For Research Use Only | Not For Clinical Use
CATAP681135773
CAS681135-77-3
Molecular Weight334.41
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Blockade of Endocannabinoid-Degrading Enzymes Attenuates Neuropathic Pain

S G Kinsey, J Z Long, S T O'Neal, R A Abdullah, J L Poklis, D L Boger, B F Cravatt, A H Lichtman

J Pharmacol Exp Ther. 2009 Sep;330(3):902-10.

PMID: 19502530

1

Design, Synthesis, and Characterization of α-ketoheterocycles That Additionally Target the Cytosolic Port Cys269 of Fatty Acid Amide Hydrolase

Katerina Otrubova, Benjamin F Cravatt, Dale L Boger

J Med Chem. 2014 Feb 13;57(3):1079-89.

PMID: 24456116

1

FAAH Inhibitor OL-135 Disrupts Contextual, but Not Auditory, Fear Conditioning in Rats

Michael A Burman, Kerribeth Szolusha, Rebecca Bind, Kristen Kerney, Dale L Boger, Edward J Bilsky

Behav Brain Res. 2016 Jul 15;308:1-5.

PMID: 27083303

1

Rational Design of Fatty Acid Amide Hydrolase Inhibitors That Act by Covalently Bonding to Two Active Site Residues

Katerina Otrubova, Monica Brown, Michael S McCormick, Gye W Han, Scott T O'Neal, Benjamin F Cravatt, Raymond C Stevens, Aron H Lichtman, Dale L Boger

J Am Chem Soc. 2013 Apr 24;135(16):6289-99.

PMID: 23581831

1

α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase: Exploration of Conformational Constraints in the Acyl Side Chain

Katharine K Duncan, Katerina Otrubova, Dale L Boger

Bioorg Med Chem. 2014 May 1;22(9):2763-70.

PMID: 24690529

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