PF-03814735

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For Research Use Only | Not For Clinical Use
CATAP942487163
CAS942487-16-3
Molecular Weight474.48
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C

1An Integrated Genomic Approach to Identify Predictive Biomarkers of Response to the Aurora Kinase Inhibitor PF-03814735

Kenneth E Hook, Scott J Garza, Maruja E Lira, Keith A Ching, Nathan V Lee, Joan Cao, Jing Yuan, Jingjing Ye, Mark Ozeck, Stephanie T Shi, Xianxian Zheng, Paul A Rejto, Julie L C Kan, James G Christensen, etc.

Mol Cancer Ther. 2012 Mar;11(3):710-9.

PMID: 22222631

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1PF-03814735, an Orally Bioavailable Small Molecule Aurora Kinase Inhibitor for Cancer Therapy

Jitesh P Jani, Joel Arcari, Vincent Bernardo, Samit K Bhattacharya, David Briere, Bruce D Cohen, Kevin Coleman, James G Christensen, Erling O Emerson, Amy Jakowski, Kenneth Hook, Gerrit Los, James D Moyer, etc.

Mol Cancer Ther. 2010 Apr;9(4):883-94.

PMID: 20354118

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1Phase I, Open-Label, Multicentre, Dose-Escalation, Pharmacokinetic and Pharmacodynamic Trial of the Oral Aurora Kinase Inhibitor PF-03814735 in Advanced Solid Tumours

Patrick Schöffski, Suzanne F Jones, Herlinde Dumez, Jeffrey R Infante, Elke Van Mieghem, Camilla Fowst, Paola Gerletti, Huiping Xu, John L Jakubczak, Patricia A English, Kristen J Pierce, Howard A Burris

Eur J Cancer. 2011 Oct;47(15):2256-64.

PMID: 21852114

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1Toward In Vitro Epigenetic Drug Design for Thyroid Cancer: The Promise of PF-03814735, an Aurora Kinase Inhibitor

Sevim Dalva-Aydemir, Cemaliye Boylu Akyerli, Şirin Kılıçturgay Yüksel, Hilal Keskin, Mustafa Cengiz Yakıcıer

OMICS. 2019 Oct;23(10):486-495.

PMID: 31549911

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