Ranolazine dihydrochloride

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For Research Use Only | Not For Clinical Use
MDL NumberMFCD03788770
Molecular Weight500.46
Description≥98% (HPLC), powder
SolubilityH2O: soluble ≥10 mg/mL
Assay≥98% (HPLC)
Colorwhite to beige
MP222-229.5 °C (lit.)
Size100MG, 500MG

1CSAHi Study: Detection of Drug-Induced Ion channel/receptor Responses, QT Prolongation, and Arrhythmia Using Multi-Electrode Arrays in Combination With Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Takashi Kitaguchi, Yuta Moriyama, Tomohiko Taniguchi, Sanae Maeda, Hiroyuki Ando, Takaaki Uda, Koji Otabe, Masao Oguchi, Shigekazu Shimizu, Hiroyuki Saito, Atsushi Toratani, Mahoko Asayama, Wataru Yamamoto, etc.

J Pharmacol Toxicol Methods. May-Jun 2017;85:73-81.

PMID: 28163191

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1Gateways to Clinical Trials

M Bayes, X Rabasseda, J R Prous

Methods Find Exp Clin Pharmacol. 2002 Apr;24(3):159-84.

PMID: 12087878

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1Protective Effects of Ranolazine in Guinea-Pig Hearts During Low-Flow Ischaemia and Their Association With Increases in Active Pyruvate Dehydrogenase

B Clarke, M Spedding, L Patmore, J G McCormack

Br J Pharmacol. 1993 Jul;109(3):748-50.

PMID: 8358570

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1The Characterization of the Metabolites of Ranolazine in Man by Liquid Chromatography Mass Spectrometry

A D Penman, J Eadie, W J Herron, M A Reilly, W R Rush, Y Liu

Rapid Commun Mass Spectrom. 1995;9(14):1418-30.

PMID: 8534891

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