SR 57227A

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For Research Use Only | Not For Clinical Use
MDL NumberMFCD01756430
Molecular Weight248.15
SolubilityH2O: soluble 9 mg/mL

1Antidepressant-like Effects of SR 57227A, a 5-HT3 Receptor Agonist, in Rodents

M Poncelet, A Perio, J Simiand, G Gout, P Soubrie, G Le Fur

J Neural Transm Gen Sect. 1995;102(2):83-90.

PMID: 8748673

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1In Vivo Modulation of the Firing Activity of Putative Slow- And Fast-Spiking Interneurons in the Medial Prefrontal Cortex by 5-HT3 Receptors in 6-hydroxydopamine-induced Parkinsonian Rats

Z H Gui, Q J Zhang, J Liu, U Ali, L B Li, Y Wang, T Wang, L Chen, C Hou, L L Fan

Neuroscience. 2010 Sep 1;169(3):1315-25.

PMID: 20576497

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1SR 57227A is a partial agonist/partial antagonist of 5-HT 3 receptor and inhibits subsequent 5-HT- or SR 57227A-induced 5-HT 3 receptor current

Yukiko Nakamura, Makoto Kondo, Yoshihisa Koyama, Shoichi Shimada

Biochem Biophys Res Commun. 2019 Jan 8;508(2):590-596.

PMID: 30509492

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1SR 57227A: A Potent and Selective Agonist at Central and Peripheral 5-HT3 Receptors in Vitro and in Vivo

A Bachy, M Héaulme, A Giudice, J C Michaud, I A Lefevre, J Souilhac, L Manara, M B Emerit, H Gozlan, M Hamon

Eur J Pharmacol. 1993 Jun 24;237(2-3):299-309.

PMID: 7689975

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1The Pyramidal Neurons in the Medial Prefrontal Cortex Show Decreased Response to 5-hydroxytryptamine-3 Receptor Stimulation in a Rodent Model of Parkinson's Disease

Qiao Jun Zhang, Li Bo Li, Xiao Lin Niu, Jian Liu, Zhen Hua Gui, Jian Jun Feng, Umar Ali, Yan Pin Hui, Zhong Heng Wu

Brain Res. 2011 Apr 12;1384:69-79.

PMID: 21291871

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