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For Research Use Only | Not For Clinical Use
MDL NumberMFCD00173799
Molecular Weight211.19
Description≥98% (HPLC), powder
SolubilityDMSO: >20 mg/mL
Assay≥98% (HPLC)
Colorwhite to beige

1[STAT3 Inhibitor Stattic Induced IL-8 Production and Cell Apotosis in THP-1 Cells by Activating ERK Pathway]

Zhilin Xiao, Meifang Chen, Mei Yang, Xiaobin Chen

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2019 Jun;35(6):498-504.

PMID: 31292053

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1PD-1 up-regulation on CD4 + T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production

Lindsay J Celada, Jonathan A Kropski, Jose D Herazo-Maya, Weifeng Luo, Amy Creecy, Andrew T Abad, Ozioma S Chioma, Grace Lee, Natalie E Hassell, Guzel I Shaginurova, Yufen Wang, Joyce E Johnson, Amy Kerrigan, etc.

Sci Transl Med. 2018 Sep 26;10(460):eaar8356.

PMID: 30257954

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1Stattic and Metformin Inhibit Brain Tumor Initiating Cells by Reducing STAT3-phosphorylation

Verena Leidgens, Judith Proske, Lisa Rauer, Sylvia Moeckel, Kathrin Renner, Ulrich Bogdahn, Markus J Riemenschneider, Martin Proescholdt, Arabel Vollmann-Zwerenz, Peter Hau, Corinna Seliger

Oncotarget. 2017 Jan 31;8(5):8250-8263.

PMID: 28030813

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1Stattic Inhibits RANKL-mediated Osteoclastogenesis by Suppressing Activation of STAT3 and NF-κB Pathways

Chang-Hong Li, Lin-Lin Xu, Lei-Lei Jian, Ruo-Han Yu, Jin-Xia Zhao, Lin Sun, Guo-Hong Du, Xiang-Yuan Liu

Int Immunopharmacol. 2018 May;58:136-144.

PMID: 29587202

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1Systemic Inhibition of IL-6/Stat3 Signalling Protects Against Experimental Osteoarthritis

Augustin Latourte, Chahrazad Cherifi, Jérémy Maillet, Hang-Korng Ea, Wafa Bouaziz, Thomas Funck-Brentano, Martine Cohen-Solal, Eric Hay, Pascal Richette

Ann Rheum Dis. 2017 Apr;76(4):748-755.

PMID: 27789465

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