CAS 18282-10-5 Tin(IV) oxide - Analytical Products / Alfa Chemistry

CAT	AP18282105
CAS	18282-10-5
Structure
MDL Number	MFCD00011244
Molecular Weight	150.71
EC Number	242-159-0
InChI Key	XOLBLPGZBRYERU-UHFFFAOYSA-N

Linear Formula

SnO2

Electrospun Tin (IV) Oxide Nanofiber Based Electrochemical Sensor for Ultra-Sensitive and Selective Detection of Atrazine in Water at Trace Levels

Patta Supraja, Suryasnata Tripathy, Siva Rama Krishna Vanjari, Vikrant Singh, Shiv Govind Singh

Biosens Bioelectron. 2019 Sep 15;141:111441.

PMID: 31229795

Oxidative stress mediated cytotoxicity of tin (IV) oxide (SnO 2) nanoparticles in human breast cancer (MCF-7) cells

Maqusood Ahamed, Mohd Javed Akhtar, M A Majeed Khan, Hisham A Alhadlaq

Colloids Surf B Biointerfaces. 2018 Dec 1;172:152-160.

PMID: 30172199

Safety Assessment of Tin(IV) Oxide as Used in Cosmetics

Wilbur Johnson Jr, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler, James G Marks Jr, Ronald C Shank, Thomas J Slaga, Paul W Snyder, F Alan Andersen

Int J Toxicol. Nov-Dec 2014;33(4 Suppl):40S-6S.

PMID: 25568164

Synthesis and Characterization of Tin(IV) Oxide Obtained by Chemical Vapor Deposition Method

Svitlana V Nagirnyak, Victoriya A Lutz, Tatiana A Dontsova, Igor M Astrelin

Nanoscale Res Lett. 2016 Dec;11(1):343.

PMID: 27456501

Tin(IV) Oxide Coatings From Hybrid organotin/polymer Nanoparticles

Rafael Muñoz-Espí, Paolo Dolcet, Torsten Rossow, Manfred Wagner, Katharina Landfester, Daniel Crespy

ACS Appl Mater Interfaces. 2011 Nov;3(11):4292-8.

PMID: 21956966

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Case Study

Preparation of Emission Layer Material Using SnO₂ Nanocomposites

Kumar, Sanjeev, and Ram Bilash Choudhary. Journal of Molecular Structure 1293 (2023): 136199.

Polyaniline (PANI) nanofibers doped with SnO₂ nanoparticles can be used as emission layer materials.
Synthesis of PANI/SnO₂ Nanocomposites: The PANI/SnO₂ nanocomposite was synthesized using an in-situ oxidative polymerization method. In this process, 2 mL of aniline monomer and 8 mL of HCl were dissolved in 70 mL of distilled water and stirred vigorously for 30 minutes. 5 wt% of the aniline monomer (equivalent to 0.102 g of SnO₂ nanoparticles) was dissolved in the above solution. Then, 4 g of APS (ammonium persulfate) was mixed with 30 mL of deionized water and stirred for 30 minutes to form a homogeneous solution. The aniline, HCl, and SnO₂ nanoparticle solution was kept in a conical flask, which was placed in an ice bath system maintained at 0-5 °C and stirred continuously on a magnetic stirrer. The APS solution was then added dropwise to the conical flask to initiate the polymerization process. The solution was maintained at 0-5 °C for 24 hours. Afterward, the solution was filtered, and the residue was washed several times alternately with water and ethanol to remove organic impurities or unpolymerized aniline monomers. The filtered precipitate was collected and dried in a vacuum oven at 60 °C for 24 hours. The dried precipitate was then ground and stored for experimental purposes. Other nanocomposites, such as 10%PS, 15%PS, and 20%PS, were synthesized using the same process, but with the concentration of SnO₂ powder adjusted accordingly.

SnO₂ Nanoparticles Induce Cytotoxicity in MCF-7 Cells

Ahamed, Maqusood, et al. Colloids and Surfaces B: Biointerfaces 172 (2018): 152-160.

Due to their unique optical and electronic properties, tin oxide nanoparticles (SnO₂ NPs) have shown potential in various applications such as solar cells, catalysts, and biomedical fields. However, information on the interaction between SnO₂ NPs and human cells remains limited.
In this study, the potential mechanisms of SnO₂ NP-induced cytotoxicity in human breast cancer (MCF-7) cells were investigated. The results showed that SnO₂ NPs induced a dose- and time-dependent decrease in cell viability, lactate dehydrogenase leakage, rounding of cell morphology, cell cycle arrest, and a reduction in mitochondrial membrane potential. It was also found that SnO₂ NPs triggered oxidative stress, as evidenced by the generation of reactive oxygen species (ROS), hydrogen peroxide (H₂O₂), and lipid peroxidation, along with a reduction in glutathione (GSH) levels and the activities of several antioxidant enzymes. Notably, the antioxidant N-acetylcysteine effectively attenuated ROS generation, GSH depletion, and cytotoxicity induced by SnO₂ NPs. The study data suggest that SnO₂ NPs induce toxicity in MCF-7 cells through oxidative stress.

Tin(IV) oxide

Preparation of Emission Layer Material Using SnO2 Nanocomposites

SnO2 Nanoparticles Induce Cytotoxicity in MCF-7 Cells

Preparation of Emission Layer Material Using SnO₂ Nanocomposites

SnO₂ Nanoparticles Induce Cytotoxicity in MCF-7 Cells