TMI-1

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For Research Use Only | Not For Clinical Use

CAT	AP287403398
CAS	287403-39-8
Structure
Molecular Weight	398.50
InChI Key	CVZIHNYAZLXRRS-HNNXBMFYSA-N

Description	≥98% (HPLC)
Solubility	DMSO: 25 mg/mL, clear
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	5MG
Storage Conditions	room temp

1Activation of Stimulator of Interferon Genes (STING) Induces ADAM17-mediated Shedding of the Immune Semaphorin SEMA4D

Kou Motani, Hidetaka Kosako

J Biol Chem. 2018 May 18;293(20):7717-7726.

PMID: 29618514

1Among Unstable Angina and Non-ST-Elevation Myocardial Infarction Patients, Transient Myocardial Ischemia and Early Invasive Treatment Are Predictors of Major In-hospital Complications

Michele M Pelter, Denise L Loranger, Teri M Kozik, Anita Kedia, Richard P Ganchan, Deborah Ganchan, Xiao Hu, Mary G Carey

J Cardiovasc Nurs. Jul-Aug 2016;31(4):E10-9.

PMID: 26646595

1Identification and Characterization of 4-[[4-(2-butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide (TMI-1), a Novel Dual Tumor Necrosis Factor-Alpha-Converting enzyme/matrix Metalloprotease Inhibitor for the Treatment of Rheumatoid Arthritis

Yuhua Zhang, Jun Xu, Jeremy Levin, Martin Hegen, Guangde Li, Heidi Robertshaw, Fionula Brennan, Terri Cummons, Dave Clarke, Nichole Vansell, Cheryl Nickerson-Nutter, Dauphine Barone, Ken Mohler, Roy Black, etc.

J Pharmacol Exp Ther. 2004 Apr;309(1):348-55.

PMID: 14718605

1Preliminary Clinical Evaluation of a Noninvasive Device for the Measurement of Coagulability in the Elderly

Yaffa Lerman, Moshe M Werber, Ilya Fine, Polina Kemelman

J Blood Med. 2011;2:113-8.

PMID: 22287870

1Tumor Selective Cytotoxic Action of a Thiomorpholin Hydroxamate Inhibitor (TMI-1) in Breast Cancer

Lynda Mezil, Carole Berruyer-Pouyet, Olivier Cabaud, Emmanuelle Josselin, Sébastien Combes, Jean-Michel Brunel, Patrice Viens, Yves Collette, Daniel Birnbaum, Marc Lopez

PLoS One. 2012;7(9):e43409.

PMID: 23028451

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