Drugs & Metabolites Standards Used in Forensic and Veterinary
Drugs refer to substances that can prevent, diagnose and treat, and their definition encompasses a wide range. For organisms, medicines can purposely adjust the physiological functions of organisms according to usage and dosage. Its metabolites refer to substances produced by the structural changes of the compound when the drug acts in the human or animal body. The metabolic process may activate the drug to produce an effect, or it may inactivate after an effect. In organisms, the use of drugs will inevitably leave metabolites.
The study of drugs and metabolites is an important part of the study of treatment mechanisms. Drug & metabolite standards are an important class of reference materials. It has important application value in the pharmaceutical industry, animal husbandry, judicial appraisal, etc. These standards can be widely used as reference materials for separation analysis, providing convenience for many identification and analysis fields.
Application fields
Forensic appraisal: Forensic pathology appraisal can identify and infer medical issues related to the law. Forensic medicine can help infer the cause of death of the deceased through anatomical examination, tissue biopsy examination, and poison examination. For some deceased patients, the drugs or drug residues in their bodies can be tested to infer the types of drugs they have taken, and then whether the disease is the cause of death. It can also test drugs or drug metabolites to infer whether the deceased was poisoned. In these identification processes, due to the uncertainty of unknown drugs, the detection range is very wide. At this time, the use of drug & metabolite standards can be used for rapid qualitative testing through the instrument and shorten the identification time.
Veterinary drug research: The safety of meat products is very important. In order to prevent diseases of livestock or increase the conversion rate of feed, the use of vaccines, antibiotics, and serum products are common in the animal husbandry industry. Veterinary medicine must ensure that it can achieve the purpose of prevention and treatment without affecting the safety and quality of meat food. Therefore, in the development of veterinary drugs, it is necessary to consider whether drug residues and drug metabolites in animals will cause quality and safety problems for meat products. Drug & metabolite standards can be used to analyze the metabolic mechanism of the veterinary drugs developed to obtain composite standard drug quality.
Why choose Alfa Chemistry?
Alfa Chemistry is one of the largest providers of drugs & metabolites standards used in for forensic and veterinary in the world and the quality assurance is of prime importance to Alfa Chemistry. The solvent from Alfa Chemistry in the world is synonymous with reliability and excellent quality. Because of the exacting nature of our business and the regulatory demands placed upon our industry, Alfa Chemistry continues to be at the forefront in terms of compliance, accreditations and certifications.
Reference
- Zhoupeng, Z.; et al. Drug metabolism in drug discovery and development [J]. Acta Pharmaceutica Sinica B 8(5) 721–732.
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