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CFTR Modulators for the Treatment of Cystic Fibrosis

Rebecca S Pettit, Chris Fellner

P T. 2014 Jul;39(7):500-11.

PMID: 25083129

Abstract:

Defects in a single gene lead to the defective proteins that cause cystic fibrosis, making the disease an ideal candidate for mutation-targeted therapy. Although ivacaftor is currently the only FDA-approved CFTR modifier, others are in development.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP38214710 VRT-532 VRT-532 38214-71-0 Price
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