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Effects of Amnesic Doses of Reserpine or Syrosingopine on Mouse Brain Acetylcholine Levels

T Palfai, L Wichlinski, H A Brown, O M Brown

Pharmacol Biochem Behav. 1986 May;24(5):1457-9.

PMID: 2873591

Abstract:

The effects of reserpine and syrosingopine on mouse whole brain acetylcholine levels were examined. At 2 or 24 hr following injection, the brains were removed and analyzed by mass spectrometry. No differences were found between drug-treated and control mice in the acetylcholine content of the brain at either time interval. The results suggest that whole brain acetylcholine levels do not predict the amnesic effects of either reserpine or syrosingopine.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP84366 Syrosingopine Syrosingopine 84-36-6 Price
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