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Functional Cellulose-Based Hydrogels as Extracellular Matrices for Tissue Engineering

Sayan Deb Dutta, Dinesh K Patel, Ki-Taek Lim

J Biol Eng. 2019 Jun 20;13:55.

PMID: 31249615

Abstract:

Cellulose-based hydrogels are immensely important for tissue engineering. In this review, we attempt to document the source, nature, and application of cellulose-based hydrogels as an extracellular matrix for tissue growth and regeneration. Hydrogels can be prepared either from native cellulose, including both bacterial and plant sources or from cellulose derivatives, such as methyl cellulose, carboxymethylcellulose, and hydroxypropylmethylcellulose or even metal ions such as silver. Cellulose-polymer composite (polymers that include natural sources including chitosan, starch, alginates, collagen, hyaluronic acid, and chitin) are an attractive, inexpensive, and advantageous structural material that is easy to use. Cellulose-based scaffolding materials are widely used in the regeneration of various tissues, such as bone, cartilage, heart, blood vessel, nerve, and liver, among others. In this review, we discuss the most important applications of cellulosic hydrogels in tissue engineering based on their structural compositions.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP9004346 Cellulose Cellulose 9004-34-6 Price
AP9004675 Methyl cellulose Methyl cellulose 9004-67-5 Price
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