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Green Electrospining of Hydroxypropyl Cellulose Nanofibres for Drug Delivery Applications

Green Electrospining of Hydroxypropyl Cellulose Nanofibres for Drug Delivery Applications

Mohamed H El-Newehy, Mehrez E El-Naggar, Saleh Alotaiby, Hany El-Hamshary, Meera Moydeen, Salem Al-Deyab

J Nanosci Nanotechnol. 2018 Feb 1;18(2):805-814.

PMID: 29448497

Abstract:

Electrospun nanofibers mats are green synthesized using hydroxypropyl cellulose (HPC) individually or in conjugation with either poly(vinyl alcohol) (PVA) or Polyvinylpyrrolidone (PVP) to enhance the mechanical properties of the nanofibers mats. Desirable attributes of the as-obtained nanofibers mats are manifested via using SEM, FT-IR, TGA and conventional tools for mechanical and physical properties. The obtained data from SEM images demonstrated that the diclofenac sodium (DS) loaded nanofibers mats did not provide significant change of the morphological structure to the mats. In addition the thermal stability and the visual and mechanical properties of PVA or PVP was dramatically enhanced with the addition of HPC. The in vitro sustained release of DS drug was controlled when loaded into electrospun nanofibers of HPC with either PVA or PVP.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP9004642	Hydroxypropyl cellulose		9004-64-2	Price

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