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Use of palladium(II) Chloride as a Colour-Forming Reagent for the Determination of N-acetyl-L-cysteine in Water and Fluimukan Injections

Use of palladium(II) Chloride as a Colour-Forming Reagent for the Determination of N-acetyl-L-cysteine in Water and Fluimukan Injections

T S Jovanović, B S Stanković

Analyst. 1989 Mar;114(3):401-3.

PMID: 2719284

Abstract:

The formation of the complex between N-acetyl-L-cysteine and palladium(II) chloride in Britton-Robinson buffer solution in the pH range 2.08-8.00 was studied. The optimum conditions for this reaction were ascertained and a spectrophotometric method was developed for the determination of N-acetyl-L-cysteine in the concentration range 4.0-65.3 micrograms ml-1, using PdCl2 as the reagent. The detection limit was 1.63 micrograms ml-1 and the relative standard deviation varied from 0.63 to 1.92%. The method was applied to the determination of N-acetyl-L-cysteine in water and in injection solutions.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP7647101	Palladium(II) chloride		7647-10-1	Price

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