CAS 7647-10-1 Palladium(II) chloride - Analytical Products / Alfa Chemistry

CAT	AP7647101
CAS	7647-10-1
MDL Number	MFCD00003558
Molecular Weight	177.33
EC Number	231-596-2
InChI Key	PIBWKRNGBLPSSY-UHFFFAOYSA-L

14-Methoxy-2,16-dioxapentacyclo[7.7.5.0.0.0]henicosa-3(8),10,12,14-tetraene-7,20-dione

Weicheng Lu, Chaomei Lian, Yan Yang, Yulin Zhu

Acta Crystallogr Sect E Struct Rep Online. 2011 Aug 1;67(Pt 8):o2108.

PMID: 22091127

Palladium and Platinum 2,4- cis-amino Azetidine and Related Complexes

Akina Yoshizawa, Antonio Feula, Andrew G Leach, Louise Male, John S Fossey

Front Chem. 2018 Jun 21;6:211.

PMID: 29977888

Palladium(II) Chloride Complexes of N,N'-Disubstituted Imidazole-2-thiones: Syntheses, Structures, and Catalytic Performances in Suzuki-Miyaura and Sonogashira Coupling Reactions

Li-Ming Zhang, Hai-Yan Li, Hong-Xi Li, David James Young, Yong Wang, Jian-Ping Lang

Inorg Chem. 2017 Sep 18;56(18):11230-11243.

PMID: 28841308

Spectrophotometric Complexation of Cephalosporins With Palladium (II) Chloride in Aqueous and Non-Aqueous Solvents

A Bagheri Gh, A Yosefi rad, M Rezvani, S Roshanzamir

Spectrochim Acta A Mol Biomol Spectrosc. 2012 Apr;89:317-21.

PMID: 22286057

Use of palladium(II) Chloride as a Colour-Forming Reagent for the Determination of N-acetyl-L-cysteine in Water and Fluimukan Injections

T S Jovanović, B S Stanković

Analyst. 1989 Mar;114(3):401-3.

PMID: 2719284

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CAT	Size	Form	Description	Price
AP7647101-1	1G, 5G, 25G, 100G	powder	99%	Inquiry
AP7647101-2	1G, 5G		99.999%	Inquiry
AP7647101-3	1G, 5G, 25G, 100G		≥99.9%	Inquiry

Case Study

Palladium Chloride (PdCl₂) in the Preparation of Polyvinyl Alcohol-Sodium Alginate Supported Catalysts for Heck Reactions

Rahman, Norul Azilah Abdul, et al. Inorganic Chemistry Communications 155 (2023): 111035.

Palladium chloride (PdCl₂) is a pivotal transition metal catalyst extensively employed in carbon-carbon coupling reactions. In this study, PdCl₂ was immobilized onto a polyvinyl alcohol-sodium alginate (PVA-SA) polymer matrix to develop a recyclable, high-performance catalyst for Heck cross-coupling reactions.
1. Catalyst Preparation: PdCl₂ (0.22 g) was combined with PVA (10 g) and SA (2 g) in 80 mL of distilled water and homogenized. The mixture underwent ultrasonic-assisted treatment using a Starsonic 60 system for optimized durations (1-5 h) to ensure uniform PdCl₂ dispersion within the polymer network.
2. Polymer Crosslinking: The PdCl₂-loaded PVA-SA mixture was subsequently dripped into a 2% CaCl₂ solution to induce gelation and ionic crosslinking, followed by storage in a chiller for 24 h.
3. Recovery and Drying: The resultant PVA-SA-PdCl₂ beads were filtered and oven-dried, producing a robust solid catalyst. Variations in SA mass were investigated to optimize PdCl₂ loading.
4. Catalytic Evaluation: The PVA-SA-PdCl₂ catalyst demonstrated complete conversion in the Heck reaction of aryl halides with styrene under mild conditions (1 mmol% catalyst, K₂CO₃ base, DMA solvent, 165 °C, 60 min). The catalyst exhibited remarkable recyclability, maintaining performance over 11 reaction cycles.
This ultrasonic-assisted one-pot strategy offers a cost-effective, environmentally friendly approach to PdCl₂ immobilization, providing a facile pathway for designing polymer-supported palladium catalysts with high efficiency and operational stability for industrially relevant C-C bond-forming reactions.

Palladium Chloride (PdCl₂) in the Preparation of SIL-PdFe Heterogeneous Catalyst for Solvent-Free Wacker Oxidation of Styrene

Yan, Yuwei, et al. Applied Surface Science 678 (2024): 161136.

Palladium chloride (PdCl₂) was employed as a central metal component in the design of a novel heterogeneous catalyst, PdCl₂-FeCl₃-imidazolium ionic liquid immobilized SBA-15 (SIL-PdFe), aimed at efficient solvent-free Wacker oxidation of styrene.
1. Support Preparation: Mesoporous SBA-15 was first synthesized and functionalized with 1-methyl-3-(chloropropyl)triethoxysilane to form imidazolium-grafted SBA-15 (SIL).
2. Catalyst Immobilization: PdCl₂ (0.25 mmol) and FeCl₃·6H₂O (0.32 mmol) were introduced into 0.5 g of SIL dispersed in 10 mL toluene and 90 mL anhydrous ethanol. The mixture was stirred at 75 °C for 24 h to enable coordination of Pd²⁺ and Fe³⁺ to the imidazolium moieties on the SBA-15 surface.
3. Purification: The solid product was recovered by filtration, followed by Soxhlet extraction with dichloromethane at 55 °C for 24 h to remove unbound surface species.
4. Drying: The resulting SIL-PdFe catalyst was dried in an air oven at 70 °C for 12 h to yield a robust, reusable solid catalyst.
Catalytic Performance: SIL-PdFe demonstrated high efficiency in the Wacker oxidation of styrene using H₂O₂ as an oxidant, achieving 95.4 % styrene conversion with 87.7 % selectivity (54.2 % acetophenone, 33.5 % benzaldehyde). The catalyst maintained activity and selectivity over multiple reuse cycles. Mechanistic studies using radical quenchers confirmed the generation of reactive oxygen species via PdCl₂-mediated H₂O₂ activation.
This work illustrates the versatile application of PdCl₂ in constructing heterogeneous ionic-liquid-based catalysts with high catalytic efficiency, recyclability, and mechanistic controllability for industrially relevant oxidation reactions.

Palladium Chloride (PdCl₂) in the Preparation of PdCl₂/AC Catalyst for the Synthesis of Salicylonitrile

Lan, Guojun, et al. Molecular Catalysis 563 (2024): 114258.

Palladium chloride (PdCl₂) was employed as the active metal in the preparation of a heterogeneous PdCl₂/activated carbon (AC) catalyst for the green synthesis of salicylonitrile via salicylamide dehydration.
1. Pd Solution Preparation: 1 g of PdCl₂ powder was dissolved in 2 mL of concentrated HCl at 60 °C and diluted with 38 mL deionized water to form an H₂PdCl₄ solution of defined concentration.
2. Support Pretreatment: High-surface-area activated carbon was dried at 120 °C for 3 h to remove moisture and impurities.
3. Impregnation: The dried AC support was impregnated with the H₂PdCl₄ solution at room temperature for 12 h to allow uniform adsorption of Pd species.
4. Drying and Activation: The impregnated sample was dried at 60 °C for 8 h, yielding a PdCl₂/AC catalyst with a theoretical Pd loading of 1 wt %.
Catalytic Application: The resulting PdCl₂/AC catalyst exhibited high catalytic activity and selectivity for converting salicylamide to salicylonitrile, achieving performance comparable to homogeneous PdCl₂ while offering the advantage of recyclability for up to seven cycles. Deactivation studies revealed that Pd(II) reduction and Pd nanoparticle agglomeration were the primary causes of activity loss.
Significance: This approach demonstrates an environmentally friendly and efficient method for industrial salicylonitrile synthesis, combining the high activity of PdCl₂ with the benefits of a recyclable heterogeneous system. The PdCl₂/AC catalyst represents a promising strategy to reduce toxic reagents, improve sustainability, and maintain high productivity in nitrile preparation.