L-(+)-2-Amino-4-phosphonobutyric acid

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For Research Use Only | Not For Clinical Use
CATAP23052815-A
CAS23052-81-5
Structure
MDL NumberMFCD00083244
Molecular Weight183.10
InChI KeyDDOQBQRIEWHWBT-VKHMYHEASA-N
Descriptionoptical purity optical purity: ≥95% (HPLC, Marfey′s reagent)
Size0.5MG, 1MG

1Inhibition of Endogenous Dopamine Release in Amphibian Retina by L-2-amino-4-phosphonobutyric Acid (L-AP4) and trans-2-aminocyclopentane-1,3-dicarboxylate (ACPD)

J H Boatright, J R Gordon, P M Iuvone

Brain Res. 1994 Jun 27;649(1-2):339-42.

PMID: 7525012

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1L-(+)-2-Amino-4-thiophosphonobutyric Acid (L-thioAP4), a New Potent Agonist of Group III Metabotropic Glutamate Receptors: Increased Distal Acidity Affords Enhanced Potency

Chelliah Selvam, Cyril Goudet, Nadia Oueslati, Jean-Philippe Pin, Francine C Acher

J Med Chem. 2007 Sep 20;50(19):4656-64.

PMID: 17722902

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1L-AP4 (L-(+)-2-amino-4-phosphonobutyric Acid) Induced Impairment of Spatial Learning in the Rat Is Antagonized by MAP4 ((S)-2-amino-2-methyl-4-phosphonobutanoic Acid)

C Hölscher, L McGlinchey, M J Rowan

Behav Brain Res. 1996 Nov;81(1-2):69-79.

PMID: 8950003

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1Micromolar L-2-amino-4-phosphonobutyric Acid Selectively Inhibits Perforant Path Synapses From Lateral Entorhinal Cortex

J F Koerner, C W Cotman

Brain Res. 1981 Jul 6;216(1):192-8.

PMID: 6266585

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1Neurotoxic Effect of High Dose of L-(+)-2-amino-3-phosphonopropionic Acid in Rats After Intracaudatal Injection

F Yuan, T Y Wang, L X Xu, Y L Sun, L Luo, B Q Qu

Acta Pharmacol Sin. 2001 Jun;22(6):556-60.

PMID: 11747764

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